Baclofen for alcohol withdrawal
نویسندگان
چکیده
منابع مشابه
Baclofen and gamma-hydroxybutyrate withdrawal.
INTRODUCTION Benzodiazepine treatment of life-threatening gamma-hydroxybutyrate (GHB) withdrawal is frequently unsatisfactory. Animal studies suggest strongly that treatment with GABA(B) agonists, such as baclofen, will be a more effective strategy. METHODS A case report from the medical intensive care unit (ICU) of the university tertiary care hospital. RESULTS A 61-year-old woman was admi...
متن کاملTreating alcohol withdrawal with oral baclofen: a randomized, double-blind, placebo-controlled trial.
BACKGROUND Abrupt cessation of alcohol intake causes habituated drinkers to experience symptoms of alcohol withdrawal syndrome (AWS). OBJECTIVE To determine the effect of the gamma-aminobutyric acid (GABA)-B agonist baclofen on the course of acute symptomatic AWS. DESIGN Prospective, randomized, double-blind, placebo-controlled clinical study. SETTING Two tertiary-care hospitals in Duluth...
متن کاملLorazepam for Alcohol Withdrawal
The index case belongs to the second category. Psychiatric illness is not a feature of men who commit filicide. In contrast, a link between maternal mental illness and filicide especially of young child has been reported (D' Orban, 1979; Marks and Kumar, 1993). Most parents show psychiatric symptoms prior to act of filicide. The guilt of killing one's own child and the hostile feelings towards ...
متن کاملAlcohol withdrawal.
Alcohol withdrawal is a common clinical condition that has a variety of complications and morbidities. The manifestations can range from mild agitation to withdrawal seizures and delirium tremens. The treatments for alcohol withdrawal include benzodiazepines, anticonvulsants, beta-blockers and antihypertensives. Although benzodiazepines are presently a first-line therapy, there is controversy r...
متن کاملR(+)-Baclofen, but Not S(−)-Baclofen, Alters Alcohol Self-Administration in Alcohol-Preferring Rats
Racemic baclofen [(±)-baclofen] has repeatedly been reported to suppress several -alcohol-motivated behaviors, including alcohol drinking and alcohol -self-administration, in rats and mice. Recent data suggested that baclofen may have bidirectional, stereospecific effects, with the more active enantiomer, R(+)-baclofen, suppressing alcohol intake and the less active enantiomer, S(-)-baclofen, s...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2017
ISSN: 1465-1858
DOI: 10.1002/14651858.cd008502.pub5